PIK3CA and APC mutations are synergistic in the development of intestinal cancers.

Deming DA, Leystra AA, Nettekoven L, Sievers C, Miller D, Middlebrooks M, Clipson L, Albrecht D, Bacher J, Washington MK, Weichert J, Halberg RB
Oncogene. 2014 33 (17): 2245-54

PMID: 23708654 · PMCID: PMC3883937 · DOI:10.1038/onc.2013.167

MeSH Terms (21)

Adenocarcinoma Adenomatous Polyposis Coli Protein Animals beta Catenin Cell Nucleus Class I Phosphatidylinositol 3-Kinases Colorectal Neoplasms Cyclin D1 Disease Models, Animal Epistasis, Genetic Female Gene Expression Humans Male Mice Mice, Inbred C57BL Mice, Transgenic Microsatellite Instability Phosphatidylinositol 3-Kinases Tumor Burden Wnt Signaling Pathway

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