Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction.

Amato RJ, Felts AS, Rodriguez AL, Venable DF, Morrison RD, Byers FW, Daniels JS, Niswender CM, Conn PJ, Lindsley CW, Jones CK, Emmitte KA
ACS Chem Neurosci. 2013 4 (8): 1217-28

PMID: 23682684 · PMCID: PMC3750677 · DOI:10.1021/cn400070k

MeSH Terms (12)

Allosteric Regulation Aminopyridines Animals Brain Cocaine-Related Disorders Disease Models, Animal Liver Phenylurea Compounds Rats Receptor, Metabotropic Glutamate 5 Structure-Activity Relationship Urea

Connections (3)

This publication is referenced by other Labnodes entities: