In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.

Gargiulo G, Cesaroni M, Serresi M, de Vries N, Hulsman D, Bruggeman SW, Lancini C, van Lohuizen M
Cancer Cell. 2013 23 (5): 660-76

PMID: 23680149 · DOI:10.1016/j.ccr.2013.03.030

MeSH Terms (17)

Activating Transcription Factor 3 Animals Bone Morphogenetic Proteins Cell Nucleus Chromatin Endoplasmic Reticulum Stress Glioblastoma Homeostasis Humans Mice Neoplastic Stem Cells Neural Stem Cells Polycomb Repressive Complex 1 Proto-Oncogene Proteins RNA Interference Signal Transduction Transforming Growth Factor beta

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