Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.

Cooks T, Pateras IS, Tarcic O, Solomon H, Schetter AJ, Wilder S, Lozano G, Pikarsky E, Forshew T, Rosenfeld N, Rozenfeld N, Harpaz N, Itzkowitz S, Harris CC, Rotter V, Gorgoulis VG, Oren M
Cancer Cell. 2013 23 (5): 634-46

PMID: 23680148 · PMCID: PMC3657134 · DOI:10.1016/j.ccr.2013.03.022

MeSH Terms (17)

Animals Azoxymethane Colitis Colon Colorectal Neoplasms Dextran Sulfate DNA Damage Genetic Predisposition to Disease Histones Humans Mice Mice, Inbred C57BL NF-kappa B Nitric Oxide Synthase Type II Protein Isoforms Tumor Necrosis Factor-alpha Tumor Suppressor Protein p53

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