B lymphocyte "original sin" in the bone marrow enhances islet autoreactivity in type 1 diabetes-prone nonobese diabetic mice.

Henry-Bonami RA, Williams JM, Rachakonda AB, Karamali M, Kendall PL, Thomas JW
J Immunol. 2013 190 (12): 5992-6003

PMID: 23677466 · PMCID: PMC3679359 · DOI:10.4049/jimmunol.1201359

MeSH Terms (18)

Amino Acid Sequence Animals Autoantigens Autoimmunity B-Lymphocytes Bone Marrow Cells Cell Separation Diabetes Mellitus, Type 1 Enzyme-Linked Immunosorbent Assay Flow Cytometry Immunoglobulin Variable Region Insulin Islets of Langerhans Lymphocyte Activation Mice Mice, Inbred NOD Molecular Sequence Data Self Tolerance

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