Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore.

Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL, Nannemann DP, Meiler J, Stewart PL, Crowe JE
PLoS One. 2013 8 (5): e61101

PMID: 23671563 · PMCID: PMC3650007 · DOI:10.1371/journal.pone.0061101

MeSH Terms (25)

Amino Acid Sequence Animals Antibodies, Monoclonal Antibodies, Viral Antigens, Viral B-Lymphocytes Caco-2 Cells Capsid Proteins Cell Line Epitopes HEK293 Cells Host-Pathogen Interactions Humans Immunoglobulin A Models, Molecular Molecular Sequence Data Neutralization Tests Protein Binding Protein Structure, Tertiary Rotavirus Rotavirus Infections Sequence Homology, Amino Acid Transcription, Genetic Virion Virus Replication

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