Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa.

Geng Y, Verhamme IM, Sun MF, Bajaj SP, Emsley J, Gailani D
J Thromb Haemost. 2013 11 (7): 1374-84

PMID: 23617568 · PMCID: PMC4158700 · DOI:10.1111/jth.12275

MeSH Terms (19)

Arginine Blood Coagulation Blood Coagulation Tests Enzyme Activation Factor IX Factor XIa Factor XI Deficiency Glycine HEK293 Cells Humans Kinetics Models, Molecular Mutation Protein Binding Protein Conformation Protein Interaction Domains and Motifs Protein Interaction Mapping Structure-Activity Relationship Transfection

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