Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity.

Shen D, Bai M, Tang R, Xu B, Ju X, Pestell RG, Achilefu S
Sci Rep. 2013 3: 1697

PMID: 23603888 · PMCID: PMC3631771 · DOI:10.1038/srep01697

MeSH Terms (10)

3-Phosphoinositide-Dependent Protein Kinases Animals Enzyme Activation Fluorescent Dyes Gene Expression Profiling MCF-7 Cells Mice Microscopy, Fluorescence, Multiphoton Oncogene Protein v-akt Protein-Serine-Threonine Kinases

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