mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers.

Deming DA, Leystra AA, Farhoud M, Nettekoven L, Clipson L, Albrecht D, Washington MK, Sullivan R, Weichert JP, Halberg RB
PLoS One. 2013 8 (4): e60709

PMID: 23593290 · PMCID: PMC3621889 · DOI:10.1371/journal.pone.0060709

MeSH Terms (20)

Animals Apoptosis Cell Proliferation Class I Phosphatidylinositol 3-Kinases Colon Colonic Neoplasms Fluorodeoxyglucose F18 Humans Male MAP Kinase Signaling System Mice Multimodal Imaging Necrosis Phosphatidylinositol 3-Kinases Positron-Emission Tomography Protein Kinase Inhibitors Signal Transduction Sirolimus Tomography, X-Ray Computed TOR Serine-Threonine Kinases

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