The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation.

Kartikasari AE, Zhou JX, Kanji MS, Chan DN, Sinha A, Grapin-Botton A, Magnuson MA, Lowry WE, Bhushan A
EMBO J. 2013 32 (10): 1393-408

PMID: 23584530 · PMCID: PMC3655467 · DOI:10.1038/emboj.2013.78

MeSH Terms (17)

Activins Animals Cell Differentiation Cells, Cultured Embryonic Stem Cells Endoderm Enhancer Elements, Genetic Feedback, Physiological Gene Expression Regulation, Developmental Humans Jumonji Domain-Containing Histone Demethylases Mice Promoter Regions, Genetic RNA Polymerase II Serine Smad2 Protein T-Box Domain Proteins

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