The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.

Ono K, Karolak MR, Ndong Jde L, Wang W, Yang X, Elefteriou F
Hum Mol Genet. 2013 22 (15): 3048-62

PMID: 23571107 · PMCID: PMC3999379 · DOI:10.1093/hmg/ddt162

MeSH Terms (13)

Animals Apoptosis Cell Proliferation Chondrocytes Chondrogenesis Extracellular Signal-Regulated MAP Kinases Gene Expression Growth Plate Mice, Knockout Neurofibromin 1 Osteogenesis Receptors, Fibroblast Growth Factor Signal Transduction

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