Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.

Gamazon ER, Lamba JK, Pounds S, Stark AL, Wheeler HE, Cao X, Im HK, Mitra AK, Rubnitz JE, Ribeiro RC, Raimondi S, Campana D, Crews KR, Wong SS, Welsh M, Hulur I, Gorsic L, Hartford CM, Zhang W, Cox NJ, Dolan ME
Blood. 2013 121 (21): 4366-76

PMID: 23538338 · PMCID: PMC3663430 · DOI:10.1182/blood-2012-10-464149

MeSH Terms (12)

Antimetabolites, Antineoplastic Apoptosis Cytarabine Drug Resistance, Neoplasm Gene Expression Regulation, Leukemic Genome-Wide Association Study Genotype Humans Leukemia, Myeloid, Acute Phenotype Polymorphism, Single Nucleotide Treatment Outcome

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