Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging.

Tang D, McKinley ET, Hight MR, Uddin MI, Harp JM, Fu A, Nickels ML, Buck JR, Manning HC
J Med Chem. 2013 56 (8): 3429-33

PMID: 23521048 · PMCID: PMC3648642 · DOI:10.1021/jm4001874

MeSH Terms (11)

Animals Biomarkers, Tumor Fluorine Radioisotopes Humans Positron-Emission Tomography Pyrazoles Pyrimidines Radiopharmaceuticals Rats Receptors, GABA Structure-Activity Relationship

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