Chiral discrimination and writhe-dependent relaxation mechanism of human topoisomerase IIα.

Seol Y, Gentry AC, Osheroff N, Neuman KC
J Biol Chem. 2013 288 (19): 13695-703

PMID: 23508957 · PMCID: PMC3650406 · DOI:10.1074/jbc.M112.444745

MeSH Terms (12)

Antigens, Neoplasm DNA, Superhelical DNA-Binding Proteins DNA Replication DNA Topoisomerases, Type II Humans Isomerism Kinetics Models, Molecular Protein Structure, Tertiary Sequence Deletion Substrate Specificity

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