Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis.

Martínez-Uña M, Varela-Rey M, Cano A, Fernández-Ares L, Beraza N, Aurrekoetxea I, Martínez-Arranz I, García-Rodríguez JL, Buqué X, Mestre D, Luka Z, Wagner C, Alonso C, Finnell RH, Lu SC, Martínez-Chantar ML, Aspichueta P, Mato JM
Hepatology. 2013 58 (4): 1296-305

PMID: 23505042 · PMCID: PMC3720726 · DOI:10.1002/hep.26399

MeSH Terms (17)

Animals Disease Models, Animal Fatty Liver Female Glycine N-Methyltransferase Homeostasis Lipid Metabolism Liver Male Membrane Proteins Mice Mice, Knockout Perilipin-2 Phosphatidylcholines Phosphatidylethanolamines S-Adenosylmethionine Triglycerides

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