Noradrenergic control of the bed nucleus of the stria terminalis in stress and reward.

Flavin SA, Winder DG
Neuropharmacology. 2013 70: 324-30

PMID: 23466330 · PMCID: PMC3644325 · DOI:10.1016/j.neuropharm.2013.02.013

The bed nucleus of the stria terminalis (BNST) is a group of inter-connected subnuclei that play critical roles in stress-reward interactions. An interesting feature of this brain region is the massive noradrenergic input that it receives. Important roles for norepinephrine in this region have been documented in a number of stress and reward related behaviors. This work has been paralleled over the last several years by efforts to understand the actions of norepinephrine on neuronal function in the region. In this review, we will summarize the current state of these research areas.

Copyright © 2013 Elsevier Ltd. All rights reserved.

MeSH Terms (11)

Adrenergic Neurons Amygdala Animals Drug-Seeking Behavior Humans Models, Neurological Receptors, Adrenergic Reward Septal Nuclei Stress, Psychological Synaptic Transmission

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