Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.

Shimada T, Murayama N, Yamazaki H, Tanaka K, Takenaka S, Komori M, Kim D, Guengerich FP
Chem Res Toxicol. 2013 26 (4): 529-37

PMID: 23432465 · PMCID: PMC3713097 · DOI:10.1021/tx3004906

MeSH Terms (14)

Amines Aryl Hydrocarbon Hydroxylases Biotransformation Carcinogens Cytochrome P-450 CYP1B1 Cytochrome P-450 CYP2A6 Environmental Pollutants Escherichia coli Genes, Bacterial Heterocyclic Compounds Humans Molecular Docking Simulation Polycyclic Aromatic Hydrocarbons Salmonella typhimurium

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