SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity.

Noah TK, Lo YH, Price A, Chen G, King E, Washington MK, Aronow BJ, Shroyer NF
Gastroenterology. 2013 144 (5): 1012-1023.e6

PMID: 23376423 · PMCID: PMC3738069 · DOI:10.1053/j.gastro.2013.01.043

MeSH Terms (18)

Adenocarcinoma Animals Apoptosis beta Catenin Cell Proliferation Colon Colonic Neoplasms Disease Progression Gene Expression Regulation, Neoplastic Humans Mice Mice, Transgenic Neoplasms, Experimental Polymerase Chain Reaction Proto-Oncogene Proteins c-ets RNA, Neoplasm Tissue Array Analysis Tumor Cells, Cultured

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