Expression profiling of 519 kinase genes in matched malignant peripheral nerve sheath tumor/plexiform neurofibroma samples is discriminatory and identifies mitotic regulators BUB1B, PBK and NEK2 as overexpressed with transformation.

Stricker TP, Henriksen KJ, Tonsgard JH, Montag AG, Krausz TN, Pytel P
Mod Pathol. 2013 26 (7): 930-43

PMID: 23370767 · DOI:10.1038/modpathol.2012.242

MeSH Terms (18)

Adolescent Adult Biomarkers, Tumor Cell Cycle Proteins Cell Transformation, Neoplastic Female Gene Expression Profiling Humans Immunohistochemistry Male Middle Aged Mitogen-Activated Protein Kinase Kinases Neurilemmoma Neurofibroma, Plexiform NIMA-Related Kinases Protein Serine-Threonine Kinases Tissue Array Analysis Young Adult

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