Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth.

Yeung CL, Ngo VN, Grohar PJ, Arnaldez FI, Asante A, Wan X, Khan J, Hewitt SM, Khanna C, Staudt LM, Helman LJ
Oncogene. 2013 32 (47): 5429-38

PMID: 23318429 · PMCID: PMC3898328 · DOI:10.1038/onc.2012.590

MeSH Terms (19)

Adaptor Proteins, Signal Transducing Animals Cell Line, Tumor Cell Proliferation Dasatinib Humans Mice Mice, Inbred NOD Mice, SCID Neoplasm Transplantation Nuclear Proteins Protein Kinase Inhibitors Proto-Oncogene Proteins c-yes Pyrimidines Rhabdomyosarcoma RNA, Small Interfering RNA Interference Signal Transduction Thiazoles

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