Pierre Ménétrier and his disease.

Coffey RJ, Tanksley J
Trans Am Clin Climatol Assoc. 2012 123: 126-33; discussion 133-4

PMID: 23303980 · PMCID: PMC3540591

In 1888, Pierre Ménétrier first described the disease that bears his name. Many of the findings he reported then remain accepted features of the disease. Based on studies performed in our laboratory over the past 20 years, we have implicated increased transforming growth factor-α (TGFα) expression and heightened epidermal growth factor receptor (EGFR) activity in the pathogenesis of Ménétrier's disease. Herein, we provide a historical perspective of this rare disorder, review our experience with Ménétrier's disease, and discuss future challenges and opportunities posed by this disorder.

MeSH Terms (7)

ErbB Receptors France Gastritis, Hypertrophic History, 19th Century History, 20th Century History, 21st Century Transforming Growth Factor alpha

Connections (2)

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