Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers.

Olaru F, Wang XP, Luo W, Ge L, Miner JH, Kleinau S, Geiger XJ, Wasiluk A, Heidet L, Kitching AR, Borza DB
J Immunol. 2013 190 (4): 1424-32

PMID: 23303673 · PMCID: PMC3563930 · DOI:10.4049/jimmunol.1202204

MeSH Terms (20)

Animals Anti-Glomerular Basement Membrane Disease Antibody Specificity Autoantibodies Autoantigens Collagen Type IV Disease Models, Animal Epitopes Female HEK293 Cells Humans Immune Tolerance Immunoglobulin G Male Mice Mice, Inbred C57BL Mice, Inbred DBA Mice, Knockout Mice, Transgenic Proteolysis

Connections (2)

This publication is referenced by other Labnodes entities:

Links