Safety, pharmacokinetics and pharmacodynamics of the anti-A33 fully-human monoclonal antibody, KRN330, in patients with advanced colorectal cancer.

Infante JR, Bendell JC, Goff LW, Jones SF, Chan E, Sudo T, Burris HA, Berlin JD
Eur J Cancer. 2013 49 (6): 1169-75

PMID: 23294608 · DOI:10.1016/j.ejca.2012.11.033

MeSH Terms (22)

Adult Aged Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Area Under Curve Colorectal Neoplasms Diarrhea Dose-Response Relationship, Drug Drug Administration Schedule Drug Resistance, Neoplasm Female Humans Immunohistochemistry Male Membrane Glycoproteins Metabolic Clearance Rate Middle Aged Nausea Neoplasm Metastasis Time Factors Treatment Outcome Vomiting

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