Multiplex genome engineering using CRISPR/Cas systems.

Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F
Science. 2013 339 (6121): 819-23

PMID: 23287718 · PMCID: PMC3795411 · DOI:10.1126/science.1231143

MeSH Terms (17)

Animals Base Sequence CRISPR-Cas Systems DNA DNA Cleavage Genetic Engineering Genetic Loci Genome Humans Inverted Repeat Sequences Mice Microarray Analysis Molecular Sequence Data Mutagenesis Recombinational DNA Repair RNA Streptococcus pyogenes

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