Non-random mtDNA segregation patterns indicate a metastable heteroplasmic segregation unit in m.3243A>G cybrid cells.

Raap AK, Jahangir Tafrechi RS, van de Rijke FM, Pyle A, Wählby C, Szuhai K, Ravelli RB, de Coo RF, Rajasimha HK, Nilsson M, Chinnery PF, Samuels DC, Janssen GM
PLoS One. 2012 7 (12): e52080

PMID: 23272214 · PMCID: PMC3525564 · DOI:10.1371/journal.pone.0052080

MeSH Terms (9)

DNA, Mitochondrial Evolution, Molecular Genetic Heterogeneity Genomic Instability Humans Mitochondrial Diseases Mitosis Mutation Point Mutation

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