A cancer-specific variant of the SLCO1B3 gene encodes a novel human organic anion transporting polypeptide 1B3 (OATP1B3) localized mainly in the cytoplasm of colon and pancreatic cancer cells.

Thakkar N, Kim K, Jang ER, Han S, Kim K, Kim D, Merchant N, Lockhart AC, Lee W
Mol Pharm. 2013 10 (1): 406-16

PMID: 23215050 · DOI:10.1021/mp3005353

MeSH Terms (14)

Biological Transport Cell Line, Tumor Colonic Neoplasms Cytoplasm Exons Genetic Variation HCT116 Cells Humans Liver Organic Anion Transporters, Sodium-Independent Pancreatic Neoplasms Protein Processing, Post-Translational Sincalide Solute Carrier Organic Anion Transporter Family Member 1B3

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