Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.

Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL, Cancer and Leukemia Group B, Cox NJ, Dolan ME
Clin Cancer Res. 2013 19 (2): 491-9

PMID: 23204130 · PMCID: PMC3549006 · DOI:10.1158/1078-0432.CCR-12-2618

MeSH Terms (13)

Antineoplastic Agents, Phytogenic Breast Neoplasms Cell Line, Tumor DNA-Binding Proteins Female Genome-Wide Association Study Humans Paclitaxel Peripheral Nervous System Diseases Polymorphism, Single Nucleotide Quantitative Trait Loci Regulatory Factor X Transcription Factors Transcription Factors

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