An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1.

Yang T, Smith JA, Leake BF, Sanders CR, Meiler J, Roden DM
Mol Pharmacol. 2013 83 (2): 481-9

PMID: 23193163 · PMCID: PMC3558809 · DOI:10.1124/mol.112.081513

MeSH Terms (15)

Alanine Allosteric Regulation Animals Binding Sites Cell Line CHO Cells Cricetinae Cysteine Heart Humans KCNQ1 Potassium Channel Models, Molecular Mutagenesis, Site-Directed Myocardium Quinidine

Connections (6)

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