Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.

Edwards JR, Perrien DS, Fleming N, Nyman JS, Ono K, Connelly L, Moore MM, Lwin ST, Yull FE, Mundy GR, Elefteriou F
J Bone Miner Res. 2013 28 (4): 960-9

PMID: 23172686 · DOI:10.1002/jbmr.1824

MeSH Terms (17)

Acetylation Aging Animals Bone and Bones Bone Remodeling Gene Deletion Gene Knockdown Techniques I-kappa B Proteins Mice NF-kappa B NF-KappaB Inhibitor alpha Organ Size Organ Specificity Osteoblasts Osteoclasts Signal Transduction Sirtuin 1

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