The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.

Ziesché E, Kettner-Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, Müller H, Newel D, Kronich P, Schneider H, Dittrich-Breiholz O, Bhaskara S, Hiebert SW, Hottiger MO, Li H, Burstein E, Schmitz ML, Kracht M
Nucleic Acids Res. 2013 41 (1): 90-109

PMID: 23087373 · PMCID: PMC3592411 · DOI:10.1093/nar/gks916

MeSH Terms (18)

Acetylation Animals Cell Line Chemokine CXCL2 Down-Regulation Histone Deacetylase Inhibitors Histone Deacetylases Humans Hydroxamic Acids Interleukin-1 Interleukin-8 Mice NF-kappa B Phosphorylation RNA Polymerase II Signal Transduction Transcription, Genetic Transcription Factor RelA

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