Ligand directed signaling differences between rodent and human κ-opioid receptors.

Schattauer SS, Miyatake M, Shankar H, Zietz C, Levin JR, Liu-Chen LY, Gurevich VV, Rieder MJ, Chavkin C
J Biol Chem. 2012 287 (50): 41595-607

PMID: 23086943 · PMCID: PMC3516711 · DOI:10.1074/jbc.M112.381368

MeSH Terms (18)

Amino Acid Substitution Analgesics, Opioid Animals Enzyme Activation HEK293 Cells Humans Ligands Male MAP Kinase Signaling System Mice Mice, Knockout Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase 3 Mutation, Missense p38 Mitogen-Activated Protein Kinases Phosphorylation Receptors, Opioid, kappa Species Specificity

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