Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants.

Holzinger ER, Grady B, Ritchie MD, Ribaudo HJ, Acosta EP, Morse GD, Gulick RM, Robbins GK, Clifford DB, Daar ES, McLaren P, Haas DW
Pharmacogenet Genomics. 2012 22 (12): 858-67

PMID: 23080225 · PMCID: PMC3614365 · DOI:10.1097/FPC.0b013e32835a450b

MeSH Terms (15)

Alkynes Anti-HIV Agents Aryl Hydrocarbon Hydroxylases Benzoxazines Clinical Protocols Cyclopropanes Cytochrome P-450 CYP2B6 Genetic Association Studies Genetic Variation Genome, Human Genome-Wide Association Study HIV Infections Humans Oxidoreductases, N-Demethylating Polymorphism, Genetic

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