The novel antiangiogenic VJ115 inhibits the NADH oxidase ENOX1 and cytoskeleton-remodeling proteins.

Venkateswaran A, Friedman DB, Walsh AJ, Skala MC, Sasi S, Rachakonda G, Crooks PA, Freeman ML, Sekhar KR
Invest New Drugs. 2013 31 (3): 535-44

PMID: 23054211 · PMCID: PMC3553230 · DOI:10.1007/s10637-012-9884-9

MeSH Terms (10)

Angiogenesis Inhibitors Cells, Cultured Cytoskeletal Proteins Humans Human Umbilical Vein Endothelial Cells Indoles NAD NADH, NADPH Oxidoreductases Proteomics Quinuclidines

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