Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.

Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK
Cell. 2012 151 (1): 138-52

PMID: 23021221 · PMCID: PMC3464914 · DOI:10.1016/j.cell.2012.06.054

MeSH Terms (15)

Animals Atherosclerosis Cholesterol Desmosterol Fatty Acids Foam Cells Gene Knockdown Techniques Leukocytes, Mononuclear Lipid Metabolism Male Mice Mice, Inbred C57BL Receptors, LDL Sterol Regulatory Element Binding Proteins Transcriptome

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