Translesion synthesis across 1,N6-(2-hydroxy-3-hydroxymethylpropan-1,3-diyl)-2'-deoxyadenosine (1,N6-γ-HMHP-dA) adducts by human and archebacterial DNA polymerases.

Kotapati S, Maddukuri L, Wickramaratne S, Seneviratne U, Goggin M, Pence MG, Villalta P, Guengerich FP, Marnett L, Tretyakova N
J Biol Chem. 2012 287 (46): 38800-11

PMID: 22977231 · PMCID: PMC3493922 · DOI:10.1074/jbc.M112.396788

MeSH Terms (19)

Archaea Base Sequence Deoxyadenosines DNA-Directed DNA Polymerase DNA Adducts DNA Damage DNA Repair DNA Replication Gene Deletion Humans Kinetics Mass Spectrometry Models, Chemical Molecular Sequence Data Oligonucleotides Recombinant Proteins Sequence Analysis, DNA Spectrometry, Mass, Electrospray Ionization Tandem Mass Spectrometry

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