A sequential mechanism for exosite-mediated factor IX activation by factor XIa.

Geng Y, Verhamme IM, Messer A, Sun MF, Smith SB, Bajaj SP, Gailani D
J Biol Chem. 2012 287 (45): 38200-9

PMID: 22961984 · PMCID: PMC3488089 · DOI:10.1074/jbc.M112.376343

MeSH Terms (20)

Arginine Binding, Competitive Binding Sites Biocatalysis Calcium Catalytic Domain Electrophoresis, Polyacrylamide Gel Factor IX Factor IXa Factor XIa HEK293 Cells Humans Kinetics Mutation Oligopeptides Protein Multimerization Proteolysis Pyrrolidonecarboxylic Acid Recombinant Proteins Substrate Specificity

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