Biomarkers of response to Akt inhibitor MK-2206 in breast cancer.

Sangai T, Akcakanat A, Chen H, Tarco E, Wu Y, Do KA, Miller TW, Arteaga CL, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F
Clin Cancer Res. 2012 18 (20): 5816-28

PMID: 22932669 · PMCID: PMC3772348 · DOI:10.1158/1078-0432.CCR-12-1141

MeSH Terms (18)

Animals Apoptosis Biomarkers, Pharmacological Breast Neoplasms Cell Line, Tumor Class I Phosphatidylinositol 3-Kinases Drug Synergism Female Heterocyclic Compounds, 3-Ring Humans In Vitro Techniques Mice Oncogene Protein v-akt Paclitaxel Phosphatidylinositol 3-Kinases Protein Kinase Inhibitors PTEN Phosphohydrolase Transplantation, Heterologous

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