A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.

Navarrete AM, Casari C, Legendre P, Marx I, Hu JR, Lenting PJ, Christophe OD, Denis CV
Blood. 2012 120 (13): 2723-32

PMID: 22915646 · DOI:10.1182/blood-2012-03-420042

MeSH Terms (21)

ADAMTS13 Protein Animals Antibodies, Monoclonal Chlorides Collagen Disease Models, Animal Enzyme-Linked Immunosorbent Assay Ferric Compounds Fibrinolytic Agents Hemorrhage Humans Metalloendopeptidases Mice Mice, Inbred C57BL Mice, Knockout Mutagenesis, Site-Directed Mutation Platelet Adhesiveness Platelet Glycoprotein GPIIb-IIIa Complex Thrombosis von Willebrand Factor

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