Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

Pruneda JN, Littlefield PJ, Soss SE, Nordquist KA, Chazin WJ, Brzovic PS, Klevit RE
Mol Cell. 2012 47 (6): 933-42

PMID: 22885007 · PMCID: PMC3462262 · DOI:10.1016/j.molcel.2012.07.001

MeSH Terms (9)

Crystallography, X-Ray Hydrogen Bonding Protein Binding Protein Conformation Protein Subunits Signal Transduction Ubiquitin Ubiquitin-Conjugating Enzymes Ubiquitin-Protein Ligases

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