Discordant cellular response to presurgical letrozole in bilateral synchronous ER+ breast cancers with a KRAS mutation or FGFR1 gene amplification.

Balko JM, Mayer IA, Sanders ME, Miller TW, Kuba MG, Meszoely IM, Wagle N, Garraway LA, Arteaga CL
Mol Cancer Ther. 2012 11 (10): 2301-5

PMID: 22879364 · PMCID: PMC3682668 · DOI:10.1158/1535-7163.MCT-12-0511

MeSH Terms (18)

Aromatase Inhibitors Base Sequence Breast Neoplasms Drug Resistance, Neoplasm Female Gene Amplification Humans Letrozole Middle Aged Molecular Sequence Data Mutation Nitriles Proto-Oncogene Proteins Proto-Oncogene Proteins p21(ras) ras Proteins Receptor, Fibroblast Growth Factor, Type 1 Receptors, Estrogen Triazoles

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