Electrophilic adduction of ubiquitin activating enzyme E1 by N,N-diethyldithiocarbamate inhibits ubiquitin activation and is accompanied by striatal injury in the rat.

Viquez OM, Caito SW, McDonald WH, Friedman DB, Valentine WM
Chem Res Toxicol. 2012 25 (11): 2310-21

PMID: 22874009 · PMCID: PMC3502677 · DOI:10.1021/tx300198h

MeSH Terms (12)

Animals Corpus Striatum Ditiocarb Enzyme Activation Enzyme Inhibitors Humans Male Models, Molecular Rats Rats, Sprague-Dawley Structure-Activity Relationship Ubiquitin-Activating Enzymes

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