Viral acute lower respiratory infections impair CD8+ T cells through PD-1.

Erickson JJ, Gilchuk P, Hastings AK, Tollefson SJ, Johnson M, Downing MB, Boyd KL, Johnson JE, Kim AS, Joyce S, Williams JV
J Clin Invest. 2012 122 (8): 2967-82

PMID: 22797302 · PMCID: PMC3408742 · DOI:10.1172/JCI62860

MeSH Terms (23)

Acute Disease Animals Antigens, Viral CD8-Positive T-Lymphocytes HLA-B7 Antigen Humans Imidazoles Immunologic Memory Influenza, Human Influenza A Virus, H1N1 Subtype Lung Metapneumovirus Mice Mice, Transgenic Paramyxoviridae Infections Programmed Cell Death 1 Receptor Pyridines Respiratory Syncytial Virus, Human Respiratory Syncytial Virus Infections Respiratory Tract Infections Signal Transduction Up-Regulation Virus Diseases

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