Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK
Proc Natl Acad Sci U S A. 2012 109 (30): 12105-10

PMID: 22773818 · PMCID: PMC3409739 · DOI:10.1073/pnas.1120914109

MeSH Terms (21)

Animals Autoantibodies Autoimmunity B-Lymphocytes, Regulatory Blotting, Western Crosses, Genetic DNA Primers Enzyme-Linked Immunosorbent Assay Flow Cytometry Hepatitis A Virus Cellular Receptor 1 Interferon-gamma Interleukin-10 Membrane Proteins Mice Mice, Inbred C57BL Mice, Mutant Strains Mucins Mutagenesis Protein Structure, Tertiary Reverse Transcriptase Polymerase Chain Reaction T-Lymphocytes

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