Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.

Jo S, Kalló I, Bardóczi Z, Arrojo e Drigo R, Zeöld A, Liposits Z, Oliva A, Lemmon VP, Bixby JL, Gereben B, Bianco AC
J Neurosci. 2012 32 (25): 8491-500

PMID: 22723689 · PMCID: PMC3752066 · DOI:10.1523/JNEUROSCI.6514-11.2012

MeSH Terms (24)

Animals Brain Ischemia Cell Hypoxia Cell Nucleus Cells, Cultured DNA Endoplasmic Reticulum Glycosylation Hippocampus HSP40 Heat-Shock Proteins Immunohistochemistry Immunoprecipitation Iodide Peroxidase Male Microscopy, Electron Middle Cerebral Artery Neurons Oxygen Consumption Polymerase Chain Reaction Rats Rats, Sprague-Dawley Receptors, Thyroid Hormone Signal Transduction Thyroid Hormones

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