Fabrication of a hybrid microfluidic system incorporating both lithographically patterned microchannels and a 3D fiber-formed microfluidic network.

Bellan LM, Kniazeva T, Kim ES, Epshteyn AA, Cropek DM, Langer R, Borenstein JT
Adv Healthc Mater. 2012 1 (2): 164-7

PMID: 22708076 · PMCID: PMC3374650 · DOI:10.1002/adhm.201100052

A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.

MeSH Terms (6)

Dimethylpolysiloxanes Equipment Design Equipment Failure Analysis Microfluidic Analytical Techniques Molecular Imprinting Photography

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