Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.

Balko JM, Cook RS, Vaught DB, Kuba MG, Miller TW, Bhola NE, Sanders ME, Granja-Ingram NM, Smith JJ, Meszoely IM, Salter J, Dowsett M, Stemke-Hale K, González-Angulo AM, Mills GB, Pinto JA, Gómez HL, Arteaga CL
Nat Med. 2012 18 (7): 1052-9

PMID: 22683778 · PMCID: PMC3693569 · DOI:10.1038/nm.2795

MeSH Terms (27)

Animals Apoptosis Breast Neoplasms Cell Survival Drug Resistance, Neoplasm Dual-Specificity Phosphatases Enzyme Activation Extracellular Signal-Regulated MAP Kinases Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Genes, Neoplasm Humans Ki-67 Antigen MAP Kinase Signaling System Mice Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinase Phosphatases Neoadjuvant Therapy Neoplasm, Residual Paraffin Embedding ras Proteins RNA, Messenger Tissue Banks Tissue Fixation Treatment Outcome

Connections (7)

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