Synthesis and antisense properties of fluoro cyclohexenyl nucleic acid (F-CeNA), a nuclease stable mimic of 2'-fluoro RNA.

Seth PP, Yu J, Jazayeri A, Pallan PS, Allerson CR, Ƙstergaard ME, Liu F, Herdewijn P, Egli M, Swayze EE
J Org Chem. 2012 77 (11): 5074-85

PMID: 22591005 · PMCID: PMC3696582 · DOI:10.1021/jo300594b

MeSH Terms (10)

Catalysis Crystallography, X-Ray Cyclohexenes Models, Molecular Molecular Structure Nucleic Acid Conformation Nucleic Acids Oligonucleotides RNA Sugar Alcohols

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