Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation.

DeGraff DJ, Clark PE, Cates JM, Yamashita H, Robinson VL, Yu X, Smolkin ME, Chang SS, Cookson MS, Herrick MK, Shariat SF, Steinberg GD, Frierson HF, Wu XR, Theodorescu D, Matusik RJ
PLoS One. 2012 7 (5): e36669

PMID: 22590586 · PMCID: PMC3349679 · DOI:10.1371/journal.pone.0036669

MeSH Terms (21)

Animals Antigens, Differentiation Biomarkers, Tumor Cadherins Carcinoma, Squamous Cell Cell Proliferation Female Gene Expression Regulation, Neoplastic Hepatocyte Nuclear Factor 3-alpha Humans Male Mice Mice, SCID Middle Aged Neoplasm Grading Neoplasm Invasiveness Neoplasm Staging Neoplasm Transplantation Rats Urinary Bladder Neoplasms Urothelium

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