Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis.

Zhou W, Dowell DR, Huckabee MM, Newcomb DC, Boswell MG, Goleniewska K, Lotz MT, Toki S, Yin H, Yao S, Natarajan C, Wu P, Sriram S, Breyer RM, Fitzgerald GA, Peebles RS
PLoS One. 2012 7 (5): e33518

PMID: 22590492 · PMCID: PMC3349674 · DOI:10.1371/journal.pone.0033518

MeSH Terms (19)

Animals Antineoplastic Agents Cell Differentiation Cells, Cultured Encephalomyelitis, Autoimmune, Experimental Epoprostenol Female Humans Iloprost Interleukin-12 Interleukin-17 Interleukin-23 Mice Mice, Inbred BALB C Mice, Knockout Platelet Aggregation Inhibitors Receptors, Epoprostenol Spinal Cord Th17 Cells

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