Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation.

Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW
Angew Chem Int Ed Engl. 2012 51 (25): 6140-3

PMID: 22566140 · PMCID: PMC3620661 · DOI:10.1002/anie.201201358

MeSH Terms (5)

Crystallography, X-Ray Genes, ras Molecular Structure Small Molecule Libraries Son of Sevenless Proteins

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